Sofosbuvir is a direct-acting antiviral medication used in combination with other drugs (like velpatasvir or ledipasvir) to treat chronic Hepatitis C virus (HCV) genotypes 1-6. It acts as a nucleotide analog inhibitor, halting viral replication. Common side effects include fatigue, headache, nausea, and insomnia. It is usually taken once daily, with or without food.
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